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Another study reported that LBP with a MW of 27.7 kDa, obtained through water extraction and alcohol precipitation, could enhance the activity of RAW264.7 macrophages at dose of 400 and 800 μg/mL, induces cell polarization (evidenced by morphological changes and increased CD86+/CD206+ markers), and bidirectionally regulates the secretion of inflammatory cytokines TNF-α and interleukin-6 (IL-6), while suppressing excessive LPS-induced inflammatory responses ( Figure 1 2.1.2 Regulation of T cell function T cells are the key effector cells of the adaptive immune system

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Beyond energy production, NAD+ plays key roles in manufacturing cholesterol, creating nucleic acids, elongating fatty acids, and regenerating glutathione, an important antioxidant